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Sinus Cocktail Shots

Desoto Family Care Clinic

Primary Care Practice located in Southaven, MS & Olive Branch, MS

When a cold makes you feel miserable or, worse, your cold turns into a sinus infection, it may be time to consider sinus cocktail shots. At Desoto Family Care Clinic, Diosan Powell, FNP, Cynthia Burchfield, FNP, and Danielle Bradley, FNP, combine several medications (the cocktail) into a shot that may relieve your symptoms and reduce sinus inflammation. To learn if a sinus cocktail shot could help you feel better, call the office in Southaven, Mississippi, or book an appointment online.

Sinus Cocktail Shots Q&A

A sinus cocktail shot is a treatment to reduce the symptoms of a common cold or a cold that turns into sinusitis.

Common cold

The common cold is caused by a virus that gets into your nose and throat and causes an infection. Everyone who has ever had a cold recognizes the symptoms:

  • Runny nose
  • Congested nose
  • Sore throat
  • Cough
  • Sneezing
  • Slight body aches
  • Low-grade fever

The common cold usually runs its course in 7-10 days.


Your sinuses are lined by tissues that produce mucus. Normally the mucus leaves the sinus through a small opening and runs into your nose.

The virus that causes the common cold can easily travel from your nose and throat into your sinuses. When that happens, the lining becomes inflamed and blocks the opening. Then the mucus gets trapped inside and an infection develops. That’s when you have sinusitis.

Though not as common, sinusitis could occur due to a bacterial infection. Or you might develop a bacterial infection in the trapped mucus after the virus clears up.

What is in a sinus cocktail shot?

Sinus cocktail shots typically contain an antihistamine and at least one steroid. If you have a bacterial infection, your shot may also contain an antibiotic. 

Because there are several types of antihistamines, steroids, and antibiotics, the exact medicines in cocktail shots tend to vary from one provider to the next.

Antihistamines relieve symptoms like nasal congestion, sneezing, a runny nose, and itching. Steroids are powerful anti-inflammatory medications, so they help to reduce swelling in the sinus and nose.

Vitamin B12 shots are also available. Or they may recommend IV vitamin therapy to strengthen your immune system and boost your body’s ability to heal your cold or sinusitis.

When would I need a sinus cocktail shot?

A sinus cocktail shot may improve your cold and sinusitis and give you better symptom relief than over-the-counter medications. In many cases, sinusitis sticks around after your cold clears up. At that point, you may want a sinus cocktail shot to ease your symptoms and help heal the sinusitis.

If you need relief from a cold or sinus infection, call Desoto Family Care Clinic or book an appointment online today.